C. Schmidtkunz: search on Z-Library

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1

Characterization of histone deacetylase 8 (HDAC8) selective inhibition reveals specific active site structural and functional determinants

Marek, Martin, Shaik, Tajith Baba, Heimburg, Tino, Chakrabarti, Alokta, LANCELOT, Julien, Ramos Morales, Elizabeth, Da Veiga, Cyrielle, Kalinin, Dmitrii V., Melesina, Jelena, Robaa, Dina, Schmidtkunz,

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.07 MB

english, 2018

2

The effect of aggregation on the separation performance of bacteria in capillary electrophoresis

Melanie Haugg, Viktoria Kaiser, Christoph Schmidtkunz, Thomas Welsch

Journal:

ELECTROPHORESIS

Year:

2009

Language:

english

File:

PDF, 199 KB

english, 2009

3

Targeting the c-Myc coiled coil with interfering peptides

Eva M. Jouaux, Karin Schmidtkunz, Kristian M. Müller, Katja M. Arndt

Journal:

Journal of Peptide Science

Year:

2008

Language:

english

File:

PDF, 350 KB

english, 2008

4

Characterization of a novelSpirillum-like bacterium that degrades ferrioxamine-type siderophores

Günther Winkelmann, Karin Schmidtkunz, Fred A. Rainey

Journal:

Year:

1996

Language:

english

File:

PDF, 400 KB

english, 1996

5

Towards an Efficient Portfolio of health investments

Hans-Walter Schmidtkunz

Journal:

Journal of Public Health (Springer)

Year:

1997

Language:

english

File:

PDF, 1022 KB

english, 1997

6

A comprehensive chemoselective and enantioselective 2D-HPLC set-up for fast enantiomer analysis of a multicomponent mixture of derivatized amino acids

T. Welsch, C. Schmidtkunz, B. Müller, F. Meier, M. Chlup, A. Köhne, M. Lämmerhofer, W. Lindner

Journal:

Analytical and Bioanalytical Chemistry

Year:

2007

Language:

english

File:

PDF, 205 KB

english, 2007

7

Electrokinetic sample extraction and enrichment: a new method for the isolation of analytes from sludge-type matrices

Christoph Schmidtkunz, Thomas Welsch

Journal:

Analytical and Bioanalytical Chemistry

Year:

2009

Language:

english

File:

PDF, 267 KB

english, 2009

8

The discovery of novel 10,11-dihydro-5H-dibenz[b,f]azepine SIRT2 inhibitors

Di Fruscia, Paolo, Ho, Ka-Kei, Laohasinnarong, Sasiwan, Khongkow, Mattaka, Kroll, Sebastian H. B., Islam, Suhail A., Sternberg, Michael J. E., Schmidtkunz, Karin, Jung, Manfred, Lam, Eric W.-F.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.30 MB

english, 2012

9

Improving the Selectivity and Confidence in the HPLC Analysis of Microcystins in Lake Sediments

Schmidtkunz, Christoph, Bernd Stich, Hans, Welsch, Thomas

Journal:

Journal of Liquid Chromatography & Related Technologies

Year:

2009

Language:

english

File:

PDF, 774 KB

english, 2009

10

Total Synthesis of (18 S )- and (18 R )-Homolargazole by Rhodium-Catalyzed Hydrocarboxylation

Schotes, Christoph, Ostrovskyi, Dmytro, Senger, Johanna, Schmidtkunz, Karin, Jung, Manfred, Breit, Bernhard

Journal:

Chemistry - A European Journal

Year:

2014

Language:

english

File:

PDF, 352 KB

english, 2014

11

Discovery of Inhibitors of Schistosoma mansoni HDAC8 by Combining Homology Modeling, Virtual Screening, and in Vitro Validation

Kannan, Srinivasaraghavan, Melesina, Jelena, Hauser, Alexander-Thomas, Chakrabarti, Alokta, Heimburg, Tino, Schmidtkunz, Karin, Walter, Alexandra, Marek, Martin, Pierce, Raymond J., Romier, Christophe

Journal:

Journal of Chemical Information and Modeling

Year:

2014

Language:

english

File:

PDF, 6.23 MB

english, 2014

12

The Discovery of a Highly Selective 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3- d ]pyrimidin-4(3 H )-one SIRT2 Inhibitor that is Neuroprotective in an in vitro Parkinson’s Disease Model

Di Fruscia, Paolo, Zacharioudakis, Emmanouil, Liu, Chang, Moniot, Sébastien, Laohasinnarong, Sasiwan, Khongkow, Mattaka, Harrison, Ian F., Koltsida, Konstantina, Reynolds, Christopher R., Schmidtkunz,

Journal:

Year:

2015

Language:

english

File:

PDF, 1.66 MB

english, 2015

13

Selective Sirt2 inhibition by ligand-induced rearrangement of the active site

Rumpf, Tobias, Schiedel, Matthias, Karaman, Berin, Roessler, Claudia, North, Brian J., Lehotzky, Attila, Oláh, Judit, Ladwein, Kathrin I., Schmidtkunz, Karin, Gajer, Markus, Pannek, Martin, Steegborn,

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 3.06 MB

english, 2015

14

Structural Basis for the Inhibition of Histone Deacetylase 8 (HDAC8), a Key Epigenetic Player in the Blood Fluke Schistosoma mansoni

Marek, Martin, Kannan, Srinivasaraghavan, Hauser, Alexander-Thomas, Moraes Mourão, Marina, Caby, Stéphanie, Cura, Vincent, Stolfa, Diana A., Schmidtkunz, Karin, Lancelot, Julien, Andrade, Luiza, Renau

Journal:

Year:

2013

Language:

english

File:

PDF, 2.23 MB

english, 2013

15

Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform

Wagner, Tobias, Greschik, Holger, Burgahn, Teresa, Schmidtkunz, Karin, Schott, Anne-Kathrin, McMillan, Joel, Baranauskienė, Lina, Xiong, Yan, Fedorov, Oleg, Jin, Jian, Oppermann, Udo, Matulis, Daumant

Journal:

Nucleic Acids Research

Year:

2016

Language:

english

File:

PDF, 2.95 MB

english, 2016

16

Preparation data of the bromodomains BRD3(1), BRD3(2), BRD4(1), and BRPF1B and crystallization of BRD4(1)-inhibitor complexes

Hügle, Martin, Lucas, Xavier, Weitzel, Gerhard, Ostrovskyi, Dmytro, Breit, Bernhard, Gerhardt, Stefan, Schmidtkunz, Karin, Jung, Manfred, Schüle, Roland, Einsle, Oliver, Günther, Stefan, Wohlwend, Dan

Journal:

Year:

2016

Language:

english

File:

PDF, 684 KB

english, 2016

17

Die bandförmige Osteoporose

Schwörer, I., Schmidtkunz, U.

Journal:

RöFo - Fortschritte auf dem Gebiet der R

Year:

1978

Language:

german

File:

PDF, 200 KB

german, 1978

18

4-Acyl Pyrroles: Mimicking Acetylated Lysines in Histone Code Reading

Lucas, Xavier, Wohlwend, Daniel, Hügle, Martin, Schmidtkunz, Karin, Gerhardt, Stefan, Schüle, Roland, Jung, Manfred, Einsle, Oliver, Günther, Stefan

Journal:

Angewandte Chemie

Year:

2013

Language:

english

File:

PDF, 1.40 MB

english, 2013

19

4-Acyl Pyrroles: Mimicking Acetylated Lysines in Histone Code Reading

Lucas, Xavier, Wohlwend, Daniel, Hügle, Martin, Schmidtkunz, Karin, Gerhardt, Stefan, Schüle, Roland, Jung, Manfred, Einsle, Oliver, Günther, Stefan

Journal:

Angewandte Chemie International Edition

Year:

2013

Language:

english

File:

PDF, 1.44 MB

english, 2013

20

Photochromic histone deacetylase inhibitors based on dithienylethenes and fulgimides

Wutz, Daniel-Fabian, Gluhacevic, Dino, Chakrabarti, Alokta, karin.schmidtkunz, Karin, Robaa, Dina, Erdmann, Frank, Romier, Christophe, Sippl, Wolfgang, Jung, Manfred, Koenig, Burkhard

Journal:

Organic & Biomolecular Chemistry

Year:

2017

Language:

english

File:

PDF, 1.12 MB

english, 2017

21

Structure-Activity Relationship of Propargylamine-Based HDAC Inhibitors

Wünsch, Matthias, Senger, Johanna, Schultheisz, Philipp, Schwarzbich, Sabrina, Schmidtkunz, Karin, Michalek, Carmela, Klaß, Michaela, Goskowitz, Stefanie, Borchert, Philipp, Praetorius, Lucas, Sippl,

Journal:

Year:

2017

Language:

english

File:

PDF, 1.83 MB

english, 2017

22

Structure-based design and biological characterization of selective histone deacetylase 8 (HDAC8) inhibitors with anti-neuroblastoma activity

Heimburg, Tino, Kolbinger, Fiona R., Zeyen, Patrik, Ghazy, Ehab, Herp, Daniel, Schmidtkunz, Karin, Melesina, Jelena, Shaik, Tajith Baba, Erdmann, Frank, Schmidt, Matthias, Romier, Christophe, Robaa, D

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.86 MB

english, 2017

23

Synthesis, crystallization studies and in vitro characterization of novel cinnamic acid derivatives as SmHDAC8 inhibitors for the treatment of Schistosomiasis

Bayer, Theresa, Chakrabarti, Alokta, Lancelot, Julien, Shaik, Tajith B., Hausmann, Kristin, Melesina, Jelena, Schmidtkunz, Karin, Marek, Martin, Erdmann, Frank, Schmidt, Matthias, Robaa, Dina, Romier,

Journal:

Year:

2018

Language:

english

File:

PDF, 1.64 MB

english, 2018

24

A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing

Simoben, Conrad, Robaa, Dina, Chakrabarti, Alokta, Schmidtkunz, Karin, Marek, Martin, Lancelot, Julien, Kannan, Srinivasaraghavan, Melesina, Jelena, Shaik, Tajith, Pierce, Raymond, Romier, Christophe,

Journal:

Year:

2018

Language:

english

File:

PDF, 4.34 MB

english, 2018

25

Front Cover: Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as Sm HDAC8 Inhibitors for the Treatment of Schistosomiasis (ChemMedChem 15/2018)

Bayer, Theresa, Chakrabarti, Alokta, Lancelot, Julien, Shaik, Tajith B., Hausmann, Kristin, Melesina, Jelena, Schmidtkunz, Karin, Marek, Martin, Erdmann, Frank, Schmidt, Matthias, Robaa, Dina, Romier,

Journal:

Year:

2018

File:

PDF, 498 KB

2018

26

Metabolic Response to XD14 Treatment in Human Breast Cancer Cell Line MCF-7

Pan, Daqiang, Kather, Michel, Willmann, Lucas, Schlimpert, Manuel, Bauer, Christoph, Lagies, Simon, Schmidtkunz, Karin, Eisenhardt, Steffen, Jung, Manfred, Günther, Stefan, Kammerer, Bernd

Journal:

International Journal of Molecular Sciences

Year:

2016

Language:

english

File:

PDF, 5.46 MB

english, 2016

27

Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 (HDAC6) Inhibitors

Vögerl, Katharina, Ong, Nghia, Senger, Johanna, Herp, Daniel, Schmidtkunz, Karin, Marek, Martin, Müller, Martin, Bartel, Karin, Shaik, Tajith Baba, Porter, Nicholas J., Robaa, Dina, Christianson, Davi

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 4.94 MB

english, 2019

28

A biomonitoring study assessing the exposure of young German adults to butylated hydroxytoluene (BHT)

Schmidtkunz, Christoph, KÃ¼pper, Katja, Weber, Till, Leng, Gabriele, Kolossa-Gehring, Marike

Journal:

International Journal of Hygiene and Environmental Health

Year:

2020

File:

PDF, 1.92 MB

2020

29

Sirtuin 1 Inhibiting Thiocyanates (S1th)âA New Class of Isotype Selective Inhibitors of NAD+ Dependent Lysine Deacetylases

WÃ¶ssner, Nathalie, Alhalabi, Zayan, GonzÃ¡lez, Jessica, Swyter, SÃ¶ren, Gan, Jin, Schmidtkunz, Karin, Zhang, Lin, Vaquero, Alejandro, Ovaa, Huib, Einsle, Oliver, Sippl, Wolfgang, Jung, Manfred

Journal:

Frontiers in Oncology

Year:

2020

File:

PDF, 1.48 MB

2020

30

2-Mercaptobenzothiazole in urine of children and adolescents in Germany â Human biomonitoring results of the German Environmental Survey 2014â2017 (GerES V)

Murawski, Aline, Schmied-Tobies, Maria I.H., Schwedler, Gerda, Rucic, Enrico, Gries, Wolfgang, Schmidtkunz, Christoph, KÃ¼pper, Katja, Leng, Gabriele, Conrad, AndrÃ©, Kolossa-Gehring, Marike

Journal:

International Journal of Hygiene and Environmental Health

Year:

2020

File:

PDF, 506 KB

2020

31

Metabolites of 4-methylbenzylidene camphor (4-MBC), butylated hydroxytoluene (BHT), and tris(2-ethylhexyl) trimellitate (TOTM) in urine of children and adolescents in Germany â human biomonitoring results of the German Environmental Survey GerES V (2014â2017)

Murawski, Aline, Schmied-Tobies, Maria I.H., Rucic, Enrico, Schmidtkunz, Christoph, KÃ¼pper, Katja, Leng, Gabriele, Eckert, Elisabeth, Kuhlmann, Laura, GÃ¶en, Thomas, Daniels, Anja, Schwedler, Gerda,

Journal:

Environmental Research

Year:

2020

File:

PDF, 137 KB

2020

32

Novel quinolone-based potent and selective HDAC6 inhibitors: synthesis, molecular modelling studies and biological investigation

Relitti, Nicola, Saraswati, A. Prasanth, Chemi, Giulia, Brindisi, Margherita, Brogi, Simone, Herp, Daniel, Schmidtkunz, Karin, Saccoccia, Fulvio, Ruberti, Giovina, Ulivieri, Cristina, Vanni, Francesca

Journal:

European Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 2.35 MB

2020

33

4-Acyl Pyrroles as Dual BET-BRD7/9 Bromodomain Inhibitors Address BETi Insensitive Human Cancer Cell Lines

HÃ¼gle, Martin, Regenass, Pierre, Warstat, Robin, Hau, Mirjam, Schmidtkunz, Karin, Lucas, Xavier, Wohlwend, Daniel, Einsle, Oliver, Jung, Manfred, Breit, Bernhard, GÃ¼nther, Stefan

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 12.30 MB

2020